Phospho-sting-s366

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August undefined, 2024

WebSTING (human) S366-p. 19781 : Phospho-STING (Ser366) (D7C3S) Rabbit mAb WebFeb 7, 2024 · TBK-independent phosphorylation of STING(S366) and its adaptor molecule TICAM2 by phospho-AKT(T308S473) augmented downstream IRF3-dependent IDO1 transcription, which was also dependent on β-catenin.

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WebThe Phospho-STING (Ser366) assay uses 2 labeled antibodies: one with a donor fluorophore, the other one with an acceptor. The first antibody is selected for its specific … WebProduct Description. This Cell Signaling Technology antibody is conjugated to Alexa Fluor ® 488 fluorescent dye and tested in-house for direct flow cytometric and immunofluorescent analysis in human cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated Phospho-STING (Ser366) (D8K6H) Rabbit mAb #40818. how to save images to pinterest

STAT2 hinders STING intracellular trafficking and reshapes its ...

WebThe work by Lehmann et al classified TNBC into six subtypes in 2011. 5 Following this, two studies at our center further identified four transcriptome-based subtypes in TNBC: luminal androgen receptor (LAR), immunomodulatory (IM), basal-like immune-suppressed (BLIS), and mesenchymal-like (MES). 6 7 Furthermore, several reports have also … WebPhospho-STING (Ser366) (E9A9K) Rabbit mAb from Cell Signaling Technology Supplier PageView Company Product Page Product Specs Company Info Reviews Back To Top … WebWestern blot - Phospho-STING-S365 Rabbit pAb (AP1199) Western blot analysis of extracts of THP-1 cells, using Phospho-STING-S365 antibody (AP1199) at 1:1000 dilution.THP-1 cells were treated by PMA (80 nM) at 37℃ for overnight. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. how to save images to database as one file

Phospho-STING (Ser366) Polyclonal Antibody (PA5-105674)

Phospho-TMEM173/STING (Ser366) Antibody Affinity Biosciences

WebOct 19, 2024 · Extended Data Fig. 9 Density maps and structural models of the AP-1–pSTING complex. The density maps (grey mesh) of AP-1 and pSTING contoured at 3σ. The protein structures fitted into the density... WebStimulator of interferon genes (STING, TMEM173, MITA) is a transmembrane adaptor protein that is a critical component of the cellular innate immune response to pathogenic cytoplasmic DNA (1,2). STING is a ubiquitously expressed protein found predominantly in the ER (1). The enzyme cGAMP synthase (cGAS) produces the second messenger cyclic … north face hooded jumpsuitWebApr 6, 2024 · Binding of TBK1 to this motif promotes the phosphorylation of S366 in the STING tail 19, which subsequently recruits and promotes the phosphorylation of the transcription factor interferon... north face hooded puffer jacket women\u0027s

"WebPhospho-STING (Ser366) Antibody (PA5-117276) in WB Western blot analysis of extracts of THP-1 cells using Phospho-STING (Ser366) Polyclonal Antibody ( Product # PA5-117276 ). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Product Details " - Phospho-sting-s366

Phospho-sting-s366

Phospho-STING (Ser366) (E9A9K) Rabbit mAb 50907S from Cell …

WebSep 23, 2024 · These findings provide insight into the mechanisms of PARPis in CAR-T cell therapy for RCC and suggest a promising adjuvant therapeutic strategy for CAR-T cell therapy in solid tumors. Supplementary Information The online version contains supplementary material available at 10.1186/s13045-021-01168-1. WebWe also generated a rabbit polyclonal antibody specific for S366-phosphorylated hSTING (p-S366); this antibody detected phosphorylated hSTING in HT-DNA transfected cells but not …

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WebPhospho-STING (Ser366) Antibody (PA5-105674) in ICC/IF. Immunofluorescent analysis of Phospho-STING (Ser366) in HepG2 cells … WebPhospho Sting S366, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 2 PubMed citations. ZERO BIAS - scores, article …

WebThe antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns. Storage: … WebOct 1, 2024 · Phosphorylation of S358 enables TBK1 to bind STING. TBK1 then trans-phosphorylates S366 of neighboring STING complexes, allowing the recruitment ... [138]. Paradoxically, introduction of the phospho-mimic S366D also strongly reduces IRF3 dimerization and IFN I production [163, 164]. This may be due to clearance of …

WebOct 24, 2013 · We conclude that phosphorylation of S366 (S365 in murine STING) occurs after autophagy and may negatively regulate STING activity to prevent sustained type I IFN production following activation by cytosolic dsDNA. Download : Download high-res image (515KB) Download : Download full-size image Figure S2. WebPhospho-STING (Ser366) Antibody (PA5-117276) in WB Western blot analysis of extracts of THP-1 cells using Phospho-STING (Ser366) Polyclonal Antibody ( Product # PA5-117276 …

WebMay 1, 2024 · (A) Heatmap shows correlation of phospho-STING (Ser_366) protein levels with cGAS and other immune-related proteins in the MD Anderson PROSPECT cohort, …

WebFeb 15, 2024 · Here, we investigated the relationship between cGAS and phospho-STING (S366) protein expression levels in treatment-naïve LUAD tumors from the MD Anderson Cancer Center (MDACC) PROSPECT trial (n=120). As expected, phospho-STING (S366) protein levels were significantly correlated with cGAS protein levels (p=0.010) (Figure 1A). north face hooded jacket greyWebPhospho-TMEM173/STING (Ser366) Antibody Phospho-TMEM173/STING (Ser366) Antibody - #AF7416 (6) (9) WB IHC IF/ICC pElisa Cites 1 /9 Western blot analysis of extracts from UV treated RAW264. View similar products>> Related products Secondary Antibodies Loading Controls Blocking Peptides Cat.#S0018 Cat.#S0006 Cat.#S0008 Cat.#S0001 Cat.#S0013 … north face hooded nuptseWebPhospho-STING (Ser366) (E9A9K) Rabbit mAb from Cell Signaling Technology Supplier PageView Company Product Page Product Specs Company Info Reviews Back To Top Biocompare is the leading resource for up-to-date product information, product reviews, and new technologies for life scientists. About Biocompare About Biocompare how to save images to google photosWebHTRF phospho-STING (S366) 64STGPEG HTRF total-STING 64NTGPEG HTRF phospho-TBK1 (S172) 64TBKPEG HTRF total-TBK1 64NTBPEG HTRF phospho-IRF3 (S386) 6FRF3PEG HTRF human IFNb 62HIFNBPEG Compounds References 2’3’ cGAMP C161-Biolog c-diAMP C088-Biolog c-diGMP C057-Biolog DMXAA D5817 –Sigma-Aldrich. how to save image to driveWeb55. A method of treating, inhibiting, reducing, ameliorating, and/or preventing a cancer and or metastasis in a subject comprising administering to a subject an adoptive immunothe how to save image to clipboardPhospho-STING (Ser366) (D7C3S) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser366 of human STING protein. Background north face hooded sweatshirt women\u0027s how to save image using pil